Anti-Testicular Receptor 4 (TR4) Antibody

Our Anti-Testicular Receptor 4 (TR4) primary antibody from PhosphoSolutions is rabbit polyclonal. It detects human, mouse, and rat Testicular Receptor 4 (TR4) and is neat serum. It is great for use in WB.



SKU: 2004-TR4

Volume: 100 µL
1-2 business days
Price:
Sale price$385.00

Product Details

Testicular Receptor 4 (TR4)
Testicular receptor 4 (TR4) is a member of the orphan nuclear receptor superfamily. Data suggests that TR4 may function as a regulator that modulates many signaling pathways. It has been suggested that TR4 is required for normal cerebellar development as TR4 knockout mice exhibit behavioral deficits in motor coordination (Chen, YT et al.,2008) and plays important roles in growth, embryonic and early postnatal survival (Collins, LL, et al., 2004).
Neat Serum
Polyclonal
IgG
WB
Rabbit
NR2C2
64 kDa
Fusion protein from the N-terminal region of mouse TR4
Human, Mouse, Rat
AB_2492265
Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cycles. Stable for at least 1 year.
Liquid
Neat Serum
Neat serum
WB: 1:1000
WB Brain: 1:1000
Unconjugated
Specific for endogenous levels of the ~64 kDa TR4 protein.
Western blots performed on each lot.
For research use only. Not intended for therapeutic or diagnostic use. Use of all products is subject to our terms and conditions, which can be viewed on our website.
After date of receipt, stable for at least 1 year at -20°C.
Blue Ice
hTAK1 antibody, Nr2c2 antibody, NR2C2_HUMAN antibody, Nuclear hormone receptor TR4 antibody, Nuclear receptor subfamily 2 group C member 2 antibody, Orphan nuclear receptor TAK1 antibody, Orphan nuclear receptor TR4 antibody, TAK1 antibody, Testicular nuclear receptor 4 antibody, Testicular receptor 4 antibody, TR2R1 antibody, TR4 antibody, TR4 nuclear hormone receptor antibody
UniProt (Human): P49116
UniProt (Immunogen Species): P49117
22026

Product Specific References for Applications and Species

Western Blot: Human
PMID Dilution Publication
21670149 not listed Cui, S., et al. 2011. Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells. Molecular and Cellular Biology, 31(16), pp.3298-3311.
17974920 not listed Tanabe, O., et al. 2007. The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription. Genes & Development, 21(21), pp.2832-2844.
17431400 not listed Tanabe, O., et al. 2007. Embryonic and fetal β‐globin gene repression by the orphan nuclear receptors, TR2 and TR4. The EMBO Journal, 26(9), pp.2295-2306.
Western Blot: Mouse
PMID Dilution Publication
24662048 not listed Cui, S., et al. 2014. PGC-1 coactivator activity is required for murine erythropoiesis. Molecular and Cellular Biology, 34(11), pp.1956-1965.
22042865 not listed Campbell, A.D., et al. 2011. Forced TR2/TR4 expression in sickle cell disease mice confers enhanced fetal hemoglobin synthesis and alleviated disease phenotypes. Proceedings of the National Academy of Sciences, 108(46), pp.18808-18813.
21670149 not listed Cui, S., et al. 2011. Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells. Molecular and Cellular Biology, 31(16), pp.3298-3311.
17974920 not listed Tanabe, O., et al. 2007. The TR2 and TR4 orphan nuclear receptors repress Gata1 transcription. Genes & Development, 21(21), pp.2832-2844.
17431400 not listed Tanabe, O., et al. 2007. Embryonic and fetal β‐globin gene repression by the orphan nuclear receptors, TR2 and TR4. The EMBO Journal, 26(9), pp.2295-2306.

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